Protein name:
Advillin ;
Alternative:
Peripheral nervous system villin-like protein (Pervin) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Associates (via C-terminus) with actin. Interacts with F-actin. Interacts with SCARF1; the interaction occurs in embryonic dorsal root ganglions at 18 dpc and induces neurite-like outgrowth.
Function:
Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in ciliogenesis.
Subcellular Location:
Cytoplasm
cytoskeleton
Cell projection
Cell projection
axon
Protein Attributes:
50:
MXXXSLSSAF | RTVTNDPGII | TWRIEKMELV | LVPLSAHGNF | YEGDCYIILS |
100:
TRRVGSLLSQ | NIHFWIGKDS | SQDEQSCAAI | YTTQLDDYLG | GSPVQHREVQ |
150:
YHESDTFRGY | FKRGIIYKKG | GVASGMKHVE | TFSYDVKRLL | HVKGKRNIRA |
200:
TEVEMSWDSF | NQGDVFLLDL | GMVIIQWNGP | ESNSGERLXX | XXXXKAMLLA |
250:
KDIRDREGGG | RAEIGVIEGD | KEAASPELMT | VLQNTLGRRS | IIKPAVPSEV |
300:
TDQQQKSTIM | LYHVSDTTGQ | LSVTEVATRP | LVQELLNHDD | CYILDQSGTK |
350:
IYVWKGKGAT | KVEKQAAMSK | ALDFIKMKGY | PSSTNVETVN | DGAESAMFKQ |
400:
LFQKWSVKDQ | TTGLGKTFSI | GKIAKIFQDK | FDVTLLHTKP | EVAAQERMVD |
450:
DGNGKVEVWR | IENLELVPVE | YQWHGFFYGG | DCYLVLYTYD | VNGKPCYILY |
500:
IWQGRHASQD | ELAASAYQAV | EVDQQFGGAP | VQVRVSMGKE | PRHFMAIFKG |
550:
KLVIYERGTS | RKGNVEPDPP | VRLFQIHGND | KSNTKAVEVS | ASASSLNSND |
600:
VFLLWTQAEH | YLWYPKGSSG | DERAMAKELA | ELLCDGDADT | VAEGQEPPEF |
650:
WDLLGGKAPY | ANDKRLQQET | LDIQVRLFEC | SNKTGRFLVT | EVTDFTQDDL |
700:
SPGDVMLLDT | WDQVFLWIGA | EANATEKEGA | LSTAQEYLVT | HPSGRDPDTP |
750:
ILIIKQGFEP | PTFTGWFLAW | DPHIWSEGKS | YEQLKNELGD | ATAIVRITTD |
800:
MKNATLSLNS | SESGPKYYPV | EVLLKSQDQE | LPEDVDPTKK | ENYLSXERDF |
829:
VSVFGITRGQ | FVSLPGWKQL | QLKKEAGLF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat Advillin
ELISA Kit for Rat Advillin
ELISA Kit for Rat Advillin
CLIA Kit for Rat Advillin
CLIA Kit for Rat Advillin
CLIA Kit for Rat Advillin
Polyclonal Antibody for Rat Advillin
Polyclonal Antibody for Rat Advillin
Polyclonal Antibody for Rat Advillin
Monoclonal Antibody for Rat Advillin
Monoclonal Antibody for Rat Advillin
Monoclonal Antibody for Rat Advillin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;ASSOCIATION WITH ACTIN;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue :
Peripheral nerve .